Enantiomer‐Selective Molecular Sensing in the Nonlinear Optical Regime via Upconverting Chiral Metamaterials

Abstract Enantiomers are chiral isomers in which the isomer's structure itself and its mirror image cannot be superimposed on each other. Enantiomer selective sensing is critical as enantiomers exhibit distinct functionalities to their image. Discriminating between by optical methods has been widely used these techniques provide nondestructive characterization, however, they constrained intrinsically small chirality of molecules. Here, a method effectively discriminate analytes nonlinear regime demonstrated, facilitated an upconverting plasmonic metamaterial. The different handedness molecules interacts with metamaterial platform, leads change circular dichroism near‐infrared region. contrast identified upconverted signal visible